Rat CTR&RAMP2 COS7
CBP71674
询 价
索取protocol
产品描述
产品数据库
| I. Background | |
| 大鼠CTR（降钙素受体）与RAMP2（受体活性修饰蛋白2）共表达时，形成AMY2型胰淀素受体（AMY2）。该复合物是胰淀素（amylin）和肾上腺髓质素（adrenomedullin）的功能性受体。RAMP2作为辅助蛋白，能改变CTR的配体特异性并协助其转运至细胞膜，从而赋予受体对胰淀素和肾上腺髓质素的响应能力。 | |
| II. Description | |
| Rat CTR&RAMP2 COS7 细胞药靶模型很好的模拟了体内 CTR&RAMP2 的信号转导过程。 |
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III. Introduction |
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| Host Cell: |
COS7 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
DMEM + 10% FBS + 2 μg/ml Puromycin+ 5 μg/ml Blasticidin
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| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): |
Functional assay for Rat CTR&RAMP2 |
| Transducer: | Gs |
| IV. Representative Data | |
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